21 October 2019

Predicting long-term survival without major disability for infants born preterm

This research investigated the long-term neurodevelopmental and cognitive outcomes for children born preterm in Western Australia between 1983 and 2010. Of the 720,901 recorded live births, 12, 083 children were diagnosed with disability, and 5,662 died without any disability diagnosis. The estimated probability of disability-free survival to 25 years was 4.1% for those born at gestational age 22 weeks, 19.7% for those born at 23 weeks, 42.4% for those born at 24 weeks, 53.0% for those born at 25 weeks, 78.3% for those born at 28 weeks, and 97.2% for those born full term (39-41 weeks).  in addition to gestational age, Apgar score, birth weight, sex, socioeconomic status, and maternal ethnicity, also had pronounced impacts on disability-free survival.