This research examined parenting stress, maternal depressive symptoms, and perceived child behaviour problems among mothers who used methamphetamine (MA) during pregnancy. Mothers who used MA during pregnancy reported more parenting stress and more depressive symptoms than a matched comparison group. There were no differences between groups on perceived child behaviour problems. Screening for potential parenting problems among mothers with a history of substance abuse is warranted. Parenting interventions targeting depressive symptoms, parenting stress, and child behaviour problems are needed for this population.