Knowledge and Resource Hub
16 September 2019

DNA deletion boosts odds of autism, especially in girls

This article discusses new research showing that DNA deletion is associated with autism. The research found that the loss of 21 genes on chromosome 3 substantially raises the risk of schizophrenia risk by  40-fold, and also increases the risk of autism by 16-fold in males and 34-fold in females. The deletion is associated with a spectrum of social disability that sometimes is severe enough to be called autism. Twenty-nine percent of carriers had autism diagnoses: (37 percent of males and 18 percent of the females) which compares with the 2.3 percent of males and 0.5 percent of females in the general population diagnosed with autism.