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09 December 2019

Association of adverse experiences and exposure to violence in childhood and adolescence with inflammatory burden in young people

This study followed 1391 young people to 18 years of age to examine if exposure to adverse experiences, stress, and violence in childhood or adolescence was associated with an increase in blood levels of inflammatory markers at 18. Individuals exposed to multiple types of violence in both childhood and adolescence had higher levels of inflammatory markers at 18 than young people who did not experience stress or violence. There was an additive effect, with an increase in the levels of inflammatory markers for each additional adverse and/or violent experience. These results suggest that adult inflammation is associated with childhood exposure to stress.